The Ascertained Sequentially Markovian Coalescent is a method to efficiently estimate pairwise coalescence times along the genome. It can be run using SNP array or whole-genome sequencing (WGS) data.


High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability. P. Palamara, J. Terhorst, Y. Song, A. Price. Nature Genetics. August 2018. [paper] [preprint] [full-text]