FastSMC

FastSMC is a method to quickly and accurately estimate pairwise identical-by-descent (IBD) regions in the genome. FastSMC estimates the age of IBD segments and scales to large biobank datasets.

Paper

Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations. J. N. Saada, G. Kalantzis, D. Shyr, F. Cooper, M. Robinson, A. Gusev†, P. F. Palamara†. Nature Communications. November 2020. [paper] [software] [data]